October 25, 2025

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10 Best over counter medications of 2025

Save up to 37% off

Best Choice

1

Advil
Advil Liqui-Gels minis Pain Reliever and Fever Reducer, Pain Medicine for Adults with Ibuprofen 200mg for Pain Relief - 200 Liquid Filled Capsules
Main highlights

Fast Absorption for Quick Relief
Advil Liqui-Gels minis provide fast absorption, delivering pain relief and fever reduction quickly and effectively.

Ideal for Tough Pain Relief
Perfect for headaches, back pain, joint pain, and minor arthritis pain, offering stronger relief than Tylenol Rapid Release Gels.

Praised for Easy Swallowing
Customers love the mini size, making them easy to swallow, even for those who struggle with larger pills.
Key specs
- dosage:As directed
- pack size:200 capsules
- active ingredient:Ibuprofen 200mg
- formulation:Liquid Filled Capsules
- flavor:N/A
9.9

Exceptional

Our Rating

9.9
simple to consume

9.7
pain management

9.3
worth the money
How do we rank?

Powerful technology We scan thousands of products and stores, analyzing reviews to find what matters most to users like you

Careful review Our team ensures quality, value, and fit based on real user feedback

Trusted insights AI and human analysis guide your decisions, reflecting real user priorities
Real users impact

Thousands of users trust our site daily

Based on millions of stores and reviews

Shoppers influence our rankings
Analyzing top stores
Value for Money

2

Amazon Basic Care
Amazon Basic Care Extra Strength Pain Relief, Acetaminophen Caplets, 500 mg, 1000 Count (Packaging may vary)
Main highlights

Effective Pain Relief and Fever Reduction
Contains 500 mg of Acetaminophen, comparable to Extra Strength Tylenol, for temporary relief from various minor aches and pains.

Versatile Use for Adults and Teens
Ideal for adults and children 12+ for pain relief and fever reduction due to colds, headaches, and more.

Cost-Effective Alternative to Brand Names
Praised for providing the same effectiveness as Tylenol at a lower price, making it a preferred choice for budget-conscious consumers.
Key specs
- dosing instructions:Adults and children 12+
- age suitability:12 years and over
- form:Caplets
- active ingredient:Acetaminophen, 500 mg
- fever reduction:Temporarily reduces fever
9.6

Exceptional

Our Rating

9.9
worth the money

9.7
simple to consume

9.7
pain management
3

Tylenol
Tylenol Extra Strength Acetaminophen Rapid Release Gels, Pain Reliever & Fever Reducer, Gelcaps with Laser-Drilled Holes for Fast Release, Gentle on Stomach, 500 mg Per Gelcap, 100 Count OTC Medicine

24% Off
Main highlights

Fast Acting Relief
100-count Tylenol Extra Strength Rapid Release Gels work quickly to relieve pain and reduce fever with 500 mg acetaminophen.

Ideal for Adults and Teens
Suitable for adults and children 12 years and older, making it versatile for family use.

Highly Praised Effectiveness
Customers appreciate the fast action and effectiveness, noting the rapid relief and long-lasting results.
Key specs
- dosing instructions:Adults and children 12+
- age suitability:12 years and older
- form:Rapid release gels
- active ingredient:Acetaminophen 500mg
- fever reduction:Helps reduce fever
9.5

Excellent

Our Rating

9.7
simple to consume

9.5
worth the money

9.5
pain management
4

Imodium
Imodium A-D Fast-Acting Anti-Diarrheal Softgels, Loperamide HCl 2 mg, Travel Essential Diarrhea Relief Medicine for Adults, 24 Count, Anti Diarrhea Pills, Ages 12+, Easy to Swallow

37% Off
Main highlights

Effective Relief
Imodium A-D Softgels provide fast, effective relief for diarrhea symptoms, restoring natural rhythm in one dose.

Ideal for Travel
Perfect for acute, active, and travelers diarrhea, suitable for ages 12 and up.

Customer Satisfaction
Customers praise its quick action and effectiveness in relieving stomach issues.
Key specs
- dosage form:softgels
- active ingredients:loperamide HCl
- symptoms relief:diarrhea symptoms
- country of origin:N/A
- package dimensions:N/A
9.4

Excellent

Our Rating

9.7
simple to consume

9.3
Flavor

8.9
worth the money
5

Ricola
Ricola Max Honey Lemon Throat Care Large Bag | Cough Suppressant Drops | Dual Action Liquid Center | Soothing Long-Lasting Relief - 34 Count (Pack of 1)

12% Off
Main highlights

Soothing Menthol and Herbal Blend
Combines menthol with Swiss mountain herbs for throat relief.

Perfect for Cold Symptoms
Ideal for relieving coughs and sore throats from colds.

Praised Liquid Center
Customers appreciate the soothing liquid center for throat coating.
Key specs
- Formulation:Lozenges
- Active Ingredient:Menthol
- Flavor:Swiss mountain herbal blend
- Country of Origin:Switzerland
- Packaging:N/A
9.2

Excellent

Our Rating
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6

Benadryl
Benadryl Ultratabs Allergy Medicine, 25 mg Diphenhydramine HCl Antihistamine Tablets For Cold & Allergy Relief of Symptoms Like Sneezing, Runny Nose, Itchy Eyes & Throat, Hay Fever, 100 Count Tablets

32% Off
Main highlights

Powerful Allergy Relief
Benadryl Ultratabs provide fast relief from sneezing, runny nose, itchy eyes, and throat.

Ideal for Seasonal Allergies
Perfect for managing symptoms from pollen, dust, mold, and pet dander.

Highly Effective
Customers praise its effectiveness in relieving allergy symptoms quickly.
9.1

Excellent

Our Rating

9.7
simple to consume

9.5
worth the money
7

Amazon Basic Care
Amazon Basic Care Ibuprofen Tablets 200 mg, Pain Reliever/Fever Reducer, Body Aches, Headache, Arthritis Pain Relief and More, 500 Count (Packaging may vary)
Main highlights

Pain Relief and Fever Reduction
Contains 200 mg ibuprofen for effective pain and fever relief.

Ideal for Various Aches
Perfect for muscular aches, arthritis, toothache, backache, and more.

Best Price and Convenience
Praised for affordability and convenience of Amazon delivery.
9.0

Excellent

Our Rating

9.9
simple to consume

9.5
pain management

9.3
worth the money
8

Amazon Basic Care
Amazon Basic Care Loperamide Hydrochloride Tablets, 2 mg, Anti-Diarrheal, 24 Count (Pack of 1) (Packaging may vary)
Main highlights

Key Features
Effective anti-diarrheal with 2 mg Loperamide HCl per tablet, gluten-free, capsule-shaped for easy intake. Comparable to Imodium A-D.

Ideal Use Cases
Optimal for controlling symptoms of diarrhea, including Travelers Diarrhea, suitable for adults and children over 6 years.

Customer Praise
Highly praised for its fast-acting relief of diarrhea, affordability, and comparable effectiveness to brand names.
8.9

Very Good

Our Rating

9.5
simple to consume

8.4
For traveling

8.4
Flavor
9

Gas-X
Gas-X Maximum Strength Gas Relief Softgels with Simethicone 250 mg - 30 Count
Main highlights

Fast Relief with Simethicone 250 mg
Provides quick relief from gas and bloating with the highest dose of simethicone available in OTC products.

Ideal for Quick Gas Relief
Perfect for adults and children over 12 needing fast, effective relief from gas and bloating.

Highly Recommended for Easy Swallowing
Customers frequently praise the small, easy-to-swallow softgel design for convenient use.
8.7

Very Good

Our Rating

9.7
simple to consume

9.3
Flavor

8.7
worth the money
10

Amazon Basic Care
Amazon Basic Care Omeprazole Delayed Release Tablets 20 mg, Treats Frequent Heartburn, Acid Reducer, Heartburn Medicine, 42 Count (Pack of 1) (Packaging may vary)
Main highlights

Effective Acid Reduction
Omeprazole 20 mg reduces stomach acid, treating frequent heartburn occurring twice a week or more.

Recommended for Regular Heartburn Sufferers
Ideal for those experiencing heartburn at least twice weekly, requiring a 14-day treatment.

Cost-Effective Prilosec Alternative
Praised for affordability and effectiveness compared to Prilosec, offering great value.
8.5

Good

Our Rating

9.9
simple to consume

9.3
Flavor

9.3
worth the money

10 Best over counter medications of 2025

1

Advil Liqui-Gels minis Pain Reliever and Fever Reducer, Pain Medicine for Adults with Ibuprofen 200mg for Pain Relief - 200 Liquid Filled Capsules

9.9

9.7

9.3

How do we rank?

How do we rank?

Analyzing top stores

2

Amazon Basic Care Extra Strength Pain Relief, Acetaminophen Caplets, 500 mg, 1000 Count (Packaging may vary)

9.9

9.7

9.7

3

Tylenol Extra Strength Acetaminophen Rapid Release Gels, Pain Reliever & Fever Reducer, Gelcaps with Laser-Drilled Holes for Fast Release, Gentle on Stomach, 500 mg Per Gelcap, 100 Count OTC Medicine

9.7

9.5

9.5

4

Imodium A-D Fast-Acting Anti-Diarrheal Softgels, Loperamide HCl 2 mg, Travel Essential Diarrhea Relief Medicine for Adults, 24 Count, Anti Diarrhea Pills, Ages 12+, Easy to Swallow

9.7

9.3

8.9

5

Ricola Max Honey Lemon Throat Care Large Bag | Cough Suppressant Drops | Dual Action Liquid Center | Soothing Long-Lasting Relief - 34 Count (Pack of 1)

6

Benadryl Ultratabs Allergy Medicine, 25 mg Diphenhydramine HCl Antihistamine Tablets For Cold & Allergy Relief of Symptoms Like Sneezing, Runny Nose, Itchy Eyes & Throat, Hay Fever, 100 Count Tablets

9.7

9.5

7

Amazon Basic Care Ibuprofen Tablets 200 mg, Pain Reliever/Fever Reducer, Body Aches, Headache, Arthritis Pain Relief and More, 500 Count (Packaging may vary)

9.9

9.5

9.3

8

Amazon Basic Care Loperamide Hydrochloride Tablets, 2 mg, Anti-Diarrheal, 24 Count (Pack of 1) (Packaging may vary)

9.5

8.4

8.4

9

Gas-X Maximum Strength Gas Relief Softgels with Simethicone 250 mg - 30 Count

9.7

9.3

8.7

10

Amazon Basic Care Omeprazole Delayed Release Tablets 20 mg, Treats Frequent Heartburn, Acid Reducer, Heartburn Medicine, 42 Count (Pack of 1) (Packaging may vary)

9.9

9.3

9.3

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